Written by Harold Oster, MD. Results suggest an inverse association between vitamin C levels and mortality due to Alzheimer’s Disease. Alzheimer’s disease is a neurodegenerative disease that leads to loss of cognitive function, disability, and death. The etiology of...
Specific Differences in Gut Microbiomes Observed in Subjects with Preclinical Alzheimer’s Disease
Written by Taylor Woosley, Staff Writer. Results of this cross-sectional observational study using data from 164 subjects in the ADRC shows that preclinical AD status was most strongly associated with microbial pathways involved in arginine and ornithine degradation...
Daily Supplementation of Folic Acid, B Vitamins, Vitamin D, and CoQ10 May Be a Potential Preventative Measure of Cognitive Impairment
Written by Taylor Woosley, Staff Writer. Results show that daily vitamin D, B vitamins, folic acid, and CoQ10 supplementation may prevent the occurrence of cognitive impairment in older adults. Dementia is characterized by a progressive deterioration of mental...
Fenugreek Seed Extract Improves Memory Status and Oxidative Stress-Related Parameters in Older Subjects
Written by Taylor Woosley, Staff Writer. 4-month supplementation of fenugreek seed extract (equivalent to 500 mg of dry extract) significantly lowered the clinical dementia rating score compared to placebo (p < 0.001). Currently 47 million people live with...
Selenium Supplementation Improves Glutathione Peroxidase Activity in Alzheimer’s Patients
Written by Taylor Woosley, Staff Writer. Analysis of a systemic review of 11 studies and a meta-analysis including 6 papers show that selenium supplementation increased MDA levels significantly by an average of 0.95 (0.44, 1.45) times (p = 0.0002). Furthermore, Se...
Higher DHA Levels Associated with Slower Decline in Alzheimer’s Disease
Written by Jessica Patella, ND. Study observations show an association between higher omega-3s, DHA and EPA and slower cognitive decline in patients with Alzheimer's disease on acetylcholinesterase inhibitors. An estimated 5.8 million Americans are living with...
Higher Serum Lutein and Zeaxanthin Levels Associated with a Lower Risk of All-Cause Dementia
Written by Taylor Woosley, Staff Writer. Study findings using data from the NHANES III Survey (1988-1994) show that serum lutein+zeaxanthin was associated with a reduced risk of all-cause dementia, with an inverse relationship being noted between serum β-cryptoxanthin...
Blueberry Consumption Improves Cognitive Executive Control in Insulin-Resistant Adults
Written by Taylor Woosley, Staff Writer. 12-week supplementation with blueberry powder (equivalent to 0.5 c of blueberries) resulted in significant improvement in lexical access and a reduction of recall intrusion errors, with a significant decline in fasting insulin...
HDL-C & Glucose Levels Measured in Early to Mid-Adulthood Associated with Alzheimer Occurrence Decades Later
Written by Taylor Woosley, Staff Writer. Study findings show that elevated glucose levels (15 mg/dL increase) in middle adulthood was associated with a 14.5% increased risk of AD while increased high density lipoprotein cholesterol (15 mg/dL increase) was associated...
B Vitamin Supplementation Improves Overall Cognitive Functioning in Non-Aspirin Users
Written by Taylor Woosley, Staff Writer. Findings suggest B-vitamin supplementation provides superior neuroprotective properties, particularly in its ability to reduce the rate of whole brain atrophy, in non-aspirin users compared to participants taking B-vitamins and...
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