Written by Taylor Woosley, Staff Writer. This study suggests that higher levels of dietary vitamin D intake, serum total 25(OH)D, and 25(OH)D3 resulted in improved cognitive performance in subjects aged 60 years and older. Life expectancy has seen an increase...
Chi3l1/YKL-40 Controls Astrocyte Circadian Clock and Alzheimer’s Disease Progression
Written by Joyce Smith, BS. This study demonstrated YKL-40 is both regulated by clock genes and involved in clearing away the potentially toxic build-up of Alzheimer’s disease (AD) proteins in the brain and that AD patients who carry a genetic variant that reduces...
Is Obstructive Sleep Apnea Severity Associated with Amyloid Beta Plaque in Brain Hippocampus?
Written by Joyce Smith, BS. Study finds that amyloid beta (Aß) plaques in the hippocampus and brainstem of people with obstructive sleep apnea (OSA) does not correlate with OSA severity. OSA affects up to 30% of adults 1,2 and often leads to decreased attention,...
Vitamin D Supplementation Protects Against Dementia Risk
Written by Joyce Smith, BS. This study suggests that in a multiethnic cohort of older adults higher vitamin D intake was associated with decreased risk of dementia. Vitamin D deficiency, even at low levels, is prevalent worldwide 1,2 and a known risk factor for...
Clinical and Bacterial Markers of Periodontitis are Associated with Alzheimer’s Disease
Written by Joyce Smith, BS. This large retrospective study examines the association between periodontal pathogens and the incidence of Alzheimer’s disease (AD), AD mortality, and incident all-cause dementia. Dementia affects 4.7% of adults aged 60 and older 1 and...
Obstructive Sleep Apnea Is Associated with Higher Brain Amyloid
Written by Joyce Smith, BS. Severe obstructive sleep apnea was associated with an increase in brain amyloid beta (Aß) protein and a greater risk of developing dementia. OSA is a common sleep disorder, affecting about 1 billion people worldwide 1 and can be 2-3 times...
Lithium NP03 Treatment for Late-Stage Amyloidosis in Rat Model of Alzheimer’s Disease
Written by Angeline A. De Leon, Staff Writer. This study demonstrates how microdose NP03 lithium reduced markers of neuroinflammation and cellular oxidative stress during the post-plaque stage of amyloid pathology in a transgenic rat model of Alzheimer’s disease....
Migraine Headaches Significantly Associated with Dementia in Women
Written by Joyce Smith, BS. In a United Kingdom study, migraine diagnoses were positively associated with all-cause dementia and Alzheimer’s disease in the elderly population, but differed substantially between men and women. In 2016 migraine headaches affected...
Sleep Quality as a Biomarker and Predictor of Alzheimer’s Disease
Written by Joyce Smith, BS. Reduced slow-wave activity and low sleep efficiency at baseline were both associated with an accelerated rate of cortical beta-amyloid plaque deposition in healthy older adults. Abundant research has provided evidence that disruptions in...
Migraine Associated with Increased Risk of Dementia in Women
Written by Angeline A. De Leon, Staff Writer. This study suggests that a history of migraines increases the risk of dementia in women, particularly in women who are sixty years of age or older. Migraine affects millions of individuals worldwide, the prevalence rate...