Vitamin D3 Repletion Improves Vascular Function and Reduces Full Length Osteopontin in Vitamin D Deficient African American Subjects

Written by Taylor Woosley, Staff Writer. Monthly supplementation of 100,000 IU of cholecalciferol was associated with a 2-fold increase in vitamin D levels, from 17 ± 5 ng/mL to 35 ± 7 ng/mL (p < 0.0001) after 12 weeks. Serum levels of log transformed flOPN were significantly reduced (p=0.03) and log FGF-23 was increased in the treated group (p = 0.04). (more…)