Vitamin D3 Repletion Improves Vascular Function and Reduces Full Length Osteopontin in Vitamin D Deficient African American Subjects

Written by Taylor Woosley, Staff Writer. Monthly supplementation of 100,000 IU of cholecalciferol was associated with a 2-fold increase in vitamin D levels, from 17 ± 5 ng/mL to 35 ± 7 ng/mL (p < 0.0001) after 12 weeks. Serum levels of log transformed flOPN were significantly reduced (p=0.03) and log FGF-23 was increased in the treated group (p = 0.04). (more…)

Insufficient or Deficient Vitamin D Levels Linked to Higher Risk of Insulin Resistance

Written by Taylor Woosley, Staff Writer. Examining vitamin D serum levels and prevalence of insulin resistance using data from the 2011-2018 National Health and Nutrition Examination Survey show that those in the lowest serum vitamin D level group had 54% greater odds of being insulin-resistant compared to those in higher serum vitamin D level groups. (more…)