Written by Chrystal Moulton, Science Writer. Researchers found that albumin and vitamin D significantly mediated the link between selenium intake and cognition (P < 0.01). Selenium is an essential trace mineral that plays a pivotal role in cognition1,2. Selenium...
Urinary Iodine and Selenium Intake as Risk Factors for Thyroid Autoimmune Disease
Written by Chrystal Moulton, Science Writer. Urinary iodine concentration between 500-800 mcg/l is significantly associated with the risk of developing thyroid autoimmunity, thyroid peroxidase antibody positivity, and thyroglobulin antibody positivity. Previous...
Combination of Selenium and Myo-Inositol Reduces Thyroid Stimulating Hormone Levels in Subjects with Hashimoto Thyroiditis
Written by Taylor Woosley, Staff Writer. 12-month supplementation of a combination of 83 µg Selenium in the form of L-Se-meth and 600 mg Myo-Inositol significantly reduced TSH levels by 38%. Hashimoto thyroiditis (HT) is one of the most common autoimmune disorders...
Selenium Effectively Reduces Insulin Resistance in Subjects with Cardiometabolic Diseases
Written by Taylor Woosley, Staff Writer. Results of a meta-analysis of 10 randomized controlled trials including 526 participants shows that selenium supplementation significantly reduced serum insulin levels (p=0.001), decreased HOMA-IR (p=0.006), and increased HDL-C...
Serum Levels of Selenium Inversely Associated with the Severity of Liver Cirrhosis
Written by Taylor Woosley, Staff Writer. Data from the 2017-2018 NHANES datasets of 5641 subjects show that, after fully multivariate adjustments, participants in the highest serum selenium quartile (>2.60 µg/L) had lower LSM values (p< 0.005) compared with...
Combined Selenium and Coenzyme Q10 Supplementation Prevents Telomere Attrition in Elderly Subjects
Written by Taylor Woosley, Staff Writer. Analyzing individual changes in LTL from inclusion to 42 months shows a significant difference in change of LTL observed in the active treatment group vs. the placebo group (delta LTL, +0.019 vs. -0.129, p=0.02). ...
Selenium Supplementation Improves Glutathione Peroxidase Activity in Alzheimer’s Patients
Written by Taylor Woosley, Staff Writer. Analysis of a systemic review of 11 studies and a meta-analysis including 6 papers show that selenium supplementation increased MDA levels significantly by an average of 0.95 (0.44, 1.45) times (p = 0.0002). Furthermore, Se...
Selenium Supplementation and Insulin Resistance
Written by Jessica Patella, ND. This study did not find an association between selenium supplementation and the development of type 2 diabetes. The CDC estimates about 1 in 10 Americans have diabetes, with 90-95% of those cases being type 2 diabetes 1. There have been...
Selenium Supplementation May Adversely Affect Prostate Cancer Risk
Written by Angeline A. De Leon, Staff Writer. This Mendelian randomization analysis does not support the use of selenium supplementation in prostate cancer prevention and suggests that supplementation might increase the risk of advanced prostate cancer and type 2...
Selenium Deficiency Linked to Increased Mortality Risk from COVID-19
Written by Joyce Smith, BS. This study reveals that selenium deficiency may be associated with more severe COVID-19 patients and supports a potential role for adjuvant selenium supplementation in selenium deficient populations. SARS-CoV-2 infection, the cause of the...
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