Vitamin D Supplementation Reduces Depressive Symptoms in Subjects with Major Depressive Disorder

Written by Taylor Woosley, Staff Writer. Significant findings of this systemic review and meta-analysis of 41 papers with a total of 53,235 participants show that subgroup analysis in participants with clinically relevant depressive symptoms (including subjects with MDD) yielded a moderate effect favoring vitamin D supplementation (Hedges’ g = −0.604, 95% CI −0.802 to −0.406, p < 0.001, I2 = 78.4%).  (more…)

Deficient or Insufficient Vitamin D Levels Associated with Depressive Symptoms in Older Adults

Written by Taylor Woosley, Staff Writer. Results of the study show that deficient and insufficient levels of serum 25-OH-D are associated with higher depression scores. The odds of a higher depression score were significantly higher in participants with insufficient 25-(OH)-D than in participants with 25-OH-D sufficiency (OR = 6.40, p < 0.001).  (more…)