Leaky Gut Syndrome and How to Support Gut Health

by | Nov 18, 2024 | Digestive Health, Recent Articles

Written by Taylor Woosley, Science Writer. Discover the causes of leaky gut syndrome and the simple nutritional changes you can make to help heal and support your gut health.

Leaky gut syndrome, or increased intestinal permeability, occurs when the intestinal lining fails to function as an effective barrier. Normally, this lining allows nutrients to pass into the bloodstream while keeping harmful substances out. However, when this barrier is compromised, undigested food particles, toxins, and bacteria can leak into the bloodstream, triggering an immune response1.

The symptoms of leaky gut syndrome can vary widely. Common symptoms include bloating, gas, abdominal pain, diarrhea, constipation, fatigue, joint pain, skin issues, and food sensitivities. It’s important to note that these symptoms can also be associated with other conditions, so consulting a healthcare professional for an accurate diagnosis is crucial.

Leaky gut syndrome can significantly impact overall health. When the intestinal barrier is compromised, harmful substances can enter the bloodstream, resulting in chronic inflammation. This ongoing inflammation can contribute to numerous health issues, including autoimmune diseases, allergies, digestive disorders, mood disorders, and skin conditions2.

Causes of Leaky Gut Syndrome

Diet plays a pivotal role in the health of our gut lining. Consuming a diet high in processed foods, refined sugars, gluten, and dairy can irritate the intestinal lining and lead to inflammation. This inflammation can weaken the tight junctions between the cells of the intestinal wall, permitting substances to leak through.

Environmental factors, such as exposure to toxins, pollutants, and certain medications, can also contribute to the development of leaky gut syndrome. Environmental toxins can disrupt the balance of beneficial bacteria in the gut, impairing gut barrier function. Additionally, long-term use of non-steroidal anti-inflammatory drugs (NSAIDs) and antibiotics may negatively impact the intestinal lining3.

Stress is another significant factor that can contribute to leaky gut syndrome. Chronic stress can disrupt the balance of gut bacteria and impair the function of the intestinal barrier. Additionally, stress can lead to increased inflammation in the body, further compromising the integrity of the gut lining.

Supplements and Herbs to Support Leaky Gut

If you’re seeking natural ways to support your gut health and alleviate the symptoms of leaky gut syndrome, incorporating certain supplements and herbs into your daily routine can be beneficial.

Probiotics: Probiotics are live bacteria and yeasts that are beneficial for your digestive system. They help restore the balance of beneficial bacteria in your gut, which can be disrupted in cases of leaky gut syndrome4. Probiotics help maintain a healthy gut flora and support the integrity of the intestinal lining5.

Aloe Vera: Aloe vera is known for its soothing properties and can be effective in reducing inflammation in the gut. It can help repair the damaged intestinal lining and promote healing6. Aloe vera can also support regular bowel movements and aid in digestion.

Turmeric: Turmeric contains curcumin, a compound with powerful anti-inflammatory properties. It can help reduce inflammation in the gut and alleviate symptoms of leaky gut syndrome7. Turmeric can be consumed in supplement form or added to your diet as a spice.

Slippery Elm: Slippery elm is an herb that has been used for centuries to treat various digestive issues. It forms a protective layer on the intestinal lining, reducing irritation and promoting healing8.

Glutamine: This crucial amino acid can regulate the expression of tight junction proteins, promoting the integrity of the intestinal cell membranes9. Furthermore, it has been shown to suppress proinflammatory signaling pathways10.

Marshmallow Root: Another herb that can be beneficial for leaky gut syndrome is marshmallow root. Marshmallow root contains mucilage, a gel-like substance that coats and soothes the digestive tract11. It can help reduce inflammation and support the healing of the intestinal lining12.

Ginger: Ginger has anti-inflammatory properties, such as gingerols, that can help soothe the inflamed lining of the intestines13. It also aids in digestion by stimulating the production of digestive enzymes, which can improve nutrient absorption and reduce the strain on the gut14. Additionally, ginger has been found to have antimicrobial effects, helping to balance the gut microbiome and prevent the growth of harmful bacteria15.

Foods to Include in a Leaky Gut Diet

It’s crucial to note that leaky gut can be aggravated by food allergens and sensitivities. Implementing an elimination diet is a helpful strategy to identify and eliminate potential triggers. After a period of elimination, it’s time to reintroduce foods one at a time to determine if they cause adverse reactions. It’s important to remember that this process should be done under the guidance of a healthcare professional to ensure proper care throughout the journey towards better gut health.

For those not experiencing food allergies or sensitivities, incorporating the right foods into your diet can play a crucial role in promoting gut health. Here are some gut-friendly foods that can help in the healing process:

  1. Gut-friendly foods that promote healing: Include foods rich in nutrients that support gut healing. Examples include bone broth, which is packed with collagen and amino acids that can aid in gut lining repair, as well as healthy fats like avocado, olive oil, and coconut oil that provide anti-inflammatory benefits.
  2. Fiber-rich foods for gut health: Fiber is essential for maintaining a healthy gut. Incorporate foods like fruits, vegetables, whole grains, and legumes into your diet. These foods provide prebiotic fibers that nourish the beneficial bacteria in your gut, improving digestion and reducing inflammation.
  3. Importance of incorporating fermented foods: Fermented foods are rich in probiotics, beneficial bacteria that can help restore the balance of gut flora. Include foods such as yogurt, kefir, sauerkraut, kimchi, and kombucha in your diet to introduce these healthy bacteria.

By implementing these nutrition changes, you can support your gut health and contribute to the healing process of leaky gut syndrome. Pairing these changes with appropriate supplements and herbs can further enhance your gut health journey.

Posted November 18, 2024.

Taylor Woosley studied biology at Purdue University before becoming a 2016 graduate of Columbia College Chicago with a major in Writing. She currently resides in Glen Ellyn, IL.

References:

  1. Chae YR, Lee YR, Kim YS, Park HY. Diet-Induced Gut Dysbiosis and Leaky Gut Syndrome. J Microbiol Biotechnol. Apr 28 2024;34(4):747-756. doi:10.4014/jmb.2312.12031
  2. Kinashi Y, Hase K. Partners in Leaky Gut Syndrome: Intestinal Dysbiosis and Autoimmunity. Frontiers in immunology. 2021;12:673708. doi:10.3389/fimmu.2021.673708
  3. d’Angelo M, Brandolini L, Catanesi M, et al. Differential Effects of Nonsteroidal Anti-Inflammatory Drugs in an In Vitro Model of Human Leaky Gut. Cells. Feb 24 2023;12(5)doi:10.3390/cells12050728
  4. Wieërs G, Belkhir L, Enaud R, et al. How Probiotics Affect the Microbiota. Front Cell Infect Microbiol. 2019;9:454. doi:10.3389/fcimb.2019.00454
  5. Mu Q, Kirby J, Reilly CM, Luo XM. Leaky Gut As a Danger Signal for Autoimmune Diseases. Frontiers in immunology. 2017;8:598. doi:10.3389/fimmu.2017.00598
  6. Maiuolo J, Musolino V, Gliozzi M, et al. Involvement of the Intestinal Microbiota in the Appearance of Multiple Sclerosis: Aloe vera and Citrus bergamia as Potential Candidates for Intestinal Health. Nutrients. Jun 29 2022;14(13)doi:10.3390/nu14132711
  7. Scazzocchio B, Minghetti L, D’Archivio M. Interaction between Gut Microbiota and Curcumin: A New Key of Understanding for the Health Effects of Curcumin. Nutrients. Aug 19 2020;12(9)doi:10.3390/nu12092499
  8. Aleman RS, Paz D, Cedillos R, Tabora M, Olson DW, Aryana K. Attributes of Culture Bacteria as Influenced by Ingredients That Help Treat Leaky Gut. Microorganisms. Mar 30 2023;11(4)doi:10.3390/microorganisms11040893
  9. Aleman RS, Moncada M, Aryana KJ. Leaky Gut and the Ingredients That Help Treat It: A Review. Molecules. Jan 7 2023;28(2)doi:10.3390/molecules28020619
  10. Perna S, Alalwan TA, Alaali Z, et al. The Role of Glutamine in the Complex Interaction between Gut Microbiota and Health: A Narrative Review. Int J Mol Sci. Oct 22 2019;20(20)doi:10.3390/ijms20205232
  11. Medicine NLo. Marshmallow. National Library of Medicine. Updated May 15, 2024. 2024.
  12. Radovanović K, Gavarić N, Aćimović M. Anti-Inflammatory Properties of Plants from Serbian Traditional Medicine. Life (Basel). Mar 24 2023;13(4)doi:10.3390/life13040874
  13. Shen CL, Wang R, Yakhnitsa V, et al. Gingerol-Enriched Ginger Supplementation Mitigates Neuropathic Pain via Mitigating Intestinal Permeability and Neuroinflammation: Gut-Brain Connection. Front Pharmacol. 2022;13:912609. doi:10.3389/fphar.2022.912609
  14. Nemati Z, Moradi Z, Alirezalu K, Besharati M, Raposo A. Impact of Ginger Root Powder Dietary Supplement on Productive Performance, Egg Quality, Antioxidant Status and Blood Parameters in Laying Japanese Quails. Int J Environ Res Public Health. Mar 15 2021;18(6)doi:10.3390/ijerph18062995
  15. Mao QQ, Xu XY, Cao SY, et al. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods. May 30 2019;8(6)doi:10.3390/foods8060185