Written by Taylor Woosley, Science Writer. Numerous studies suggest that CBD may offer various positive effects on the body, making it a favored choice for those seeking natural remedies. Explore some of the key health benefits associated with CBD,
As the interest in natural remedies grows, cannabidiol (CBD) has become a popular choice for enhancing health and addressing various diseases. Derived from the cannabis plant, CBD is known for its therapeutic properties without the psychoactive effects associated with tetrahydrocannabinol (THC)1. But what exactly is cannabidiol, and how can it benefit your health?
As early as the 19th century, interest in the pharmacokinetics of the active constituents of cannabis, the cannabinoids, began to illuminate the potential benefits for human health2. CBD is one of over 100 cannabinoids found in cannabis. It is typically extracted from hemp plants, which are a variety of cannabis cultivated for their low THC content. Once extracted, CBD can be formulated into various products, such as oils, capsules, topicals, and edibles, each offering different concentrations of CBD for various purposes.
Health Benefits of CBD
Numerous studies suggest that CBD may offer various positive effects on the body, making it a favored choice for those seeking natural remedies. Let’s explore some of the key health benefits associated with CBD:
Pain Relief: One of the most recognized benefits of CBD is its potential to alleviate pain. CBD interacts with the body’s endocannabinoid system, which regulates pain perception3. By binding to certain receptors in the brain and immune system, CBD may help reduce pain and inflammation. Furthermore, studies have shown that CBD can also be effective in managing chronic pain conditions such as fibromyalgia due to its ability to suppress pro-inflammatory cytokine expression4.
Joint Health and Inflammation: CBD has emerged as a promising natural remedy for managing joint-related issues and inflammation. Recent studies have shown that CBD possesses anti-inflammatory properties, making it favorable for those suffering from conditions like arthritis. By inhibiting specific enzymes responsible for inflammation, CBD has been found to provide relief and improve joint mobility5.
Mental Health Disorders: CBD has gained attention for its potential to alleviate symptoms of mental health disorders like anxiety and depression. Recent studies have shown that CBD interacts with the brain’s serotonin receptors, which play a crucial role in regulating mood and emotions6. By modulating serotonin levels, CBD may help improve mood and reduce anxiety symptoms. Additionally, CBD’s anti-inflammatory properties could also contribute to its potential benefits for mental health. Although more research is necessary to fully understand the mechanisms, CBD holds promise as a natural alternative for supporting mental well-being.
Cancer-Related Symptoms: CBD has been found to have potential benefits in relieving symptoms associated with cancer and its treatment. In addition to its potential in reducing chemotherapy-induced nausea and vomiting, CBD has shown promise in alleviating pain and improving sleep quality for cancer patients7. While it is important to note that CBD should not be considered a replacement for conventional treatments, it can be used as a complementary therapy to provide additional relief. Further research is needed to fully understand the extent of CBD’s effects on cancer-related symptoms.
CBD for Neuroprotection
CBD may protect the brain through its anti-inflammatory and antioxidant effects. Inflammation and oxidative stress contribute to the progression of neurodegenerative diseases like Alzheimer’s, Parkinson’s, and multiple sclerosis. CBD has been found to be highly effective in decreasing inflammation and oxidative damage, potentially slowing down these degenerative processes.
Moreover, CBD shows promise in alleviating symptoms of neurodegenerative diseases, such as tremors, muscle stiffness, and cognitive impairment8. CBD’s interaction with the endocannabinoid system may regulate neurotransmitter function and promote neurogenesis, the growth of new neurons9.
Aside from its potential benefits for neurodegenerative diseases, CBD also promotes overall brain health by enhancing neuroplasticity, the brain’s ability to adapt and form new connections10. This can improve learning, memory, and cognitive function.
While more research is needed to fully understand CBD’s neuroprotective effects, current findings are promising.
CBD for Mental Wellness
Anxiety and depression are prevalent mental health conditions that significantly impact daily life. Studies show that CBD may help alleviate symptoms of anxiety and depression by interacting with brain receptors that regulate mood and emotions11. CBD has potential anti-anxiety and antidepressant effects, providing a natural alternative for those seeking relief.
PTSD, or post-traumatic stress disorder, can arise after experiencing a traumatic event, causing symptoms like flashbacks, nightmares, and intrusive thoughts. Preliminary animal studies suggest that CBD may help manage PTSD symptoms by reducing anxiety and improving sleep12.
CBD’s potential as a treatment for addiction is another area of interest. Substance abuse and addiction are complex issues with severe consequences. Research indicates that CBD may have therapeutic properties aiding addiction recovery13. Findings from a double-blind, placebo-controlled study suggest that CBD may modulate brain circuits associated with addiction, reducing drug cravings and withdrawal symptoms14.
CBD Dosage and Safety
When using CBD for health and disease, determining the right dosage is crucial for optimal results. CBD dosage can vary based on factors such as body weight, the condition’s severity, and the consumption method.
CBD is generally well-tolerated, but like any supplement or medication, it can have side effects. These are typically mild and may include dry mouth, diarrhea, fatigue, and changes in appetite. It is advisable to start with a low dosage and gradually increase it until the desired effects are achieved. Consult with a healthcare professional before using CBD, especially if you have underlying medical conditions or are taking other medications.
Posted September 20, 2024.
Taylor Woosley studied biology at Purdue University before becoming a 2016 graduate of Columbia College Chicago with a major in Writing. She currently resides in Glen Ellyn, IL.
References:
- Hall N, James B, Bhuiyan MAN, Crane E, Falgout C, Murnane KS. Topical cannabidiol is well tolerated in individuals with a history of elite physical performance and chronic lower extremity pain. J Cannabis Res. Mar 30 2023;5(1):11. doi:10.1186/s42238-023-00179-8
- Sivesind TE, Maghfour J, Rietcheck H, Kamel K, Malik AS, Dellavalle RP. Cannabinoids for the Treatment of Dermatologic Conditions. JID Innov. Mar 2022;2(2):100095. doi:10.1016/j.xjidi.2022.100095
- Atalay S, Jarocka-Karpowicz I, Skrzydlewska E. Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland). Dec 25 2019;9(1)doi:10.3390/antiox9010021
- Umpreecha C, Bhalang K, Charnvanich D, Luckanagul J. Efficacy and safety of topical 0.1% cannabidiol for managing recurrent aphthous ulcers: a randomized controlled trial. BMC complementary medicine and therapies. Feb 20 2023;23(1):57. doi:10.1186/s12906-023-03886-0
- Lowin T, Tingting R, Zurmahr J, Classen T, Schneider M, Pongratz G. Cannabidiol (CBD): a killer for inflammatory rheumatoid arthritis synovial fibroblasts. Cell Death Dis. Sep 1 2020;11(8):714. doi:10.1038/s41419-020-02892-1
- de Almeida DL, Devi LA. Diversity of molecular targets and signaling pathways for CBD. Pharmacol Res Perspect. Dec 2020;8(6):e00682. doi:10.1002/prp2.682
- O’Brien K. Cannabidiol (CBD) in Cancer Management. Cancers (Basel). Feb 10 2022;14(4)doi:10.3390/cancers14040885
- Cooray R, Gupta V, Suphioglu C. Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson’s and Alzheimer’s Diseases: a Review. Mol Neurobiol. Nov 2020;57(11):4878-4890. doi:10.1007/s12035-020-02054-6
- Castillo-Arellano J, Canseco-Alba A, Cutler SJ, León F. The Polypharmacological Effects of Cannabidiol. Molecules. Apr 6 2023;28(7)doi:10.3390/molecules28073271
- Schouten M, Dalle S, Mantini D, Koppo K. Cannabidiol and brain function: current knowledge and future perspectives. Front Pharmacol. 2023;14:1328885. doi:10.3389/fphar.2023.1328885
- Batalla A, Bos J, Postma A, Bossong MG. The Impact of Cannabidiol on Human Brain Function: A Systematic Review. Front Pharmacol. 2020;11:618184. doi:10.3389/fphar.2020.618184
- García-Gutiérrez MS, Navarrete F, Gasparyan A, Austrich-Olivares A, Sala F, Manzanares J. Cannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders. Biomolecules. Nov 19 2020;10(11)doi:10.3390/biom10111575
- Navarrete F, García-Gutiérrez MS, Gasparyan A, Austrich-Olivares A, Manzanares J. Role of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders. Front Pharmacol. 2021;12:626010. doi:10.3389/fphar.2021.626010
- Sholler DJ, Schoene L, Spindle TR. Therapeutic Efficacy of Cannabidiol (CBD): A Review of the Evidence from Clinical Trials and Human Laboratory Studies. Curr Addict Rep. Sep 2020;7(3):405-412. doi:10.1007/s40429-020-00326-8