by Becky | Aug 24, 2023 | 2023, Aging, Alzheimer's Disease, Brain Health
Written by Taylor Woosley, Staff Writer. Results of this cross-sectional observational study using data from 164 subjects in the ADRC shows that preclinical AD status was most strongly associated with microbial pathways involved in arginine and ornithine degradation (P < 0.001), while the pathways most associated with healthy status was glutamate degradation (P < 0.001). (more…)
by Becky | Mar 20, 2023 | 2023, Alzheimer's Disease, Botanicals, Brain Health, Fenugreek
Written by Taylor Woosley, Staff Writer. 4-month supplementation of fenugreek seed extract (equivalent to 500 mg of dry extract) significantly lowered the clinical dementia rating score compared to placebo (p < 0.001). (more…)
by Becky | Sep 27, 2022 | Alzheimer's Disease, Brain Health, Minerals, Selenium
Written by Taylor Woosley, Staff Writer. Analysis of a systemic review of 11 studies and a meta-analysis including 6 papers show that selenium supplementation increased MDA levels significantly by an average of 0.95 (0.44, 1.45) times (p = 0.0002). Furthermore, Se only supplementation significantly increased GPX activity by an average of 0.95 (0.59, 1.31) times (p = 0.00001). (more…)
by Becky | Aug 1, 2022 | Alzheimer's Disease, Brain Health, DHA, EPA (Eicosapentaenoic Acid), Omega - 3
Written by Jessica Patella, ND. Study observations show an association between higher omega-3s, DHA and EPA and slower cognitive decline in patients with Alzheimer’s disease on acetylcholinesterase inhibitors. (more…)
by Becky | Jun 10, 2022 | 2022, Alzheimer's Disease, Blood Lipids, Blood Sugar, Brain Health
Written by Taylor Woosley, Staff Writer. Study findings show that elevated glucose levels (15 mg/dL increase) in middle adulthood was associated with a 14.5% increased risk of AD while increased high density lipoprotein cholesterol (15 mg/dL increase) was associated with a 15.4% decreased risk of AD in early adulthood and a 17.9% decreased risk in middle adulthood. (more…)
by Becky | Mar 7, 2022 | 2021, Alzheimer's Disease, Brain Health, Cognitive Health, Vitamin B - General
Written by Taylor Woosley, Staff Writer. Findings suggest B-vitamin supplementation provides superior neuroprotective properties, particularly in its ability to reduce the rate of whole brain atrophy, in non-aspirin users compared to participants taking B-vitamins and aspirin. (more…)
by Becky | Nov 22, 2021 | 2021, Aging, Alzheimer's Disease, Brain Health, Cognitive Health, Vitamin D - Mental Health
Written by Taylor Woosley, Staff Writer. This study suggests that higher levels of dietary vitamin D intake, serum total 25(OH)D, and 25(OH)D3 resulted in improved cognitive performance in subjects aged 60 years and older. (more…)
by Becky | Feb 23, 2021 | 2020, Alzheimer's Disease, Brain Health, Sleep
Written by Joyce Smith, BS. This study demonstrated YKL-40 is both regulated by clock genes and involved in clearing away the potentially toxic build-up of Alzheimer’s disease (AD) proteins in the brain and that AD patients who carry a genetic variant that reduces YKL-40 levels maintain their cognitive faculties longer than those individuals without the variant. (more…)
by Becky | Jan 12, 2021 | 2020, Alzheimer's Disease, Brain Health, Sleep
Written by Joyce Smith, BS. Study finds that amyloid beta (Aß) plaques in the hippocampus and brainstem of people with obstructive sleep apnea (OSA) does not correlate with OSA severity. (more…)
by Becky | Dec 15, 2020 | 2020, Alzheimer's Disease, Brain Health, Oral Health
Written by Joyce Smith, BS. This large retrospective study examines the association between periodontal pathogens and the incidence of Alzheimer’s disease (AD), AD mortality, and incident all-cause dementia. (more…)
by Becky | Dec 7, 2020 | 2020, Alzheimer's Disease, Brain Health, Sleep
Written by Joyce Smith, BS. Severe obstructive sleep apnea was associated with an increase in brain amyloid beta (Aß) protein and a greater risk of developing dementia. (more…)
by Becky | Oct 13, 2020 | 2020, Alzheimer's Disease, Brain Health
Written by Angeline A. De Leon, Staff Writer. This study demonstrates how microdose NP03 lithium reduced markers of neuroinflammation and cellular oxidative stress during the post-plaque stage of amyloid pathology in a transgenic rat model of Alzheimer’s disease. (more…)
by Becky | Oct 8, 2020 | 2019, Alzheimer's Disease, Brain Health, Headaches
Written by Joyce Smith, BS. In a United Kingdom study, migraine diagnoses were positively associated with all-cause dementia and Alzheimer’s disease in the elderly population, but differed substantially between men and women. (more…)
by Becky | Sep 29, 2020 | 2020, Alzheimer's Disease, Brain Health, Sleep
Written by Joyce Smith, BS. Reduced slow-wave activity and low sleep efficiency at baseline were both associated with an accelerated rate of cortical beta-amyloid plaque deposition in healthy older adults. (more…)
by Becky | Aug 26, 2020 | 2019, Alzheimer's Disease, Brain Health, Headaches, Women's Health
Written by Angeline A. De Leon, Staff Writer. This study suggests that a history of migraines increases the risk of dementia in women, particularly in women who are sixty years of age or older.
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by Becky | Aug 4, 2020 | 2020, Alzheimer's Disease, Brain Health, DHA, Omega - 3
Written by Joyce Smith, BS. This study suggests that a minimum dose of two grams per day of docosahexaenoic acid (DHA) is required to ensure adequate delivery to the brain, particularly for those individuals who carry the APOE4 allele. (more…)
by Becky | Jul 28, 2020 | 2019, Alzheimer's Disease, Brain Health, Headaches
Written by Joyce Smith, BS. Study finds that migraine history is a significant risk factor for Alzheimer disease (AD) and all‐cause dementia, but not vascular dementia in a population of older independently-living adults. (more…)
by Becky | Jun 22, 2020 | Alzheimer's Disease, Brain Health
Written by Patrick Massey, MD, PhD. A recent medical study concluded that people who repetitively have negative thoughts are at an increased risk of developing Alzheimer’s disease later in life. (more…)
by Becky | May 18, 2020 | 2020, Alzheimer's Disease, Brain Health, Flavonoids
Written by Joyce Smith, BS. Twenty years of consuming small amounts of flavonoid rich foods such as apples, berries and tea doubled and even quadrupled the risk of developing Alzheimer’s disease (AD) and Alzheimer’s disease related dementias (ADRD) compared to consuming higher amounts of flavonoid rich foods. (more…)
by Becky | May 5, 2020 | 2020, Alzheimer's Disease, Brain Health, Cardiovascular Health
Written by Angeline A. De Leon, Staff Writer. This study explores the anti-inflammatory capability of beta-hydroxybutyrate (β-OHB) and the mechanism by which it protects against Alzheimer’s disease (AD) and atherosclerosis. (more…)