Raspberry Extract (Ellagic Acid) – Informed Opinion

By Gene Bruno, MS, MHS – Dean of Academics, Huntington College of Health Sciences.  Antimutagenic agents such as Ellagic Acid inhibit the mutagenic process (a process where a cell could develop into a cancer).  Posted May 4, 2011.

Ellagic acid (EA) is a phenolic compound with antimutagenic and anticarcinogenic properties. It occurs naturally in some foods such as strawberries, raspberries, grapes, black currants and walnuts. (1) In this formula, EA is standardized at a level of 1% from raspberry extract.

When a cell is exposed to a mutagen and consequently assumes a mutagenic form, it may develop into a cancer. The value of antimutagnic agents such as EA, is that they inhibit the mutagenic process. In one study, the greatest inhibitory effect of EA on a potent mutagen occurred when they were incubated together. (2) In another study, EA demonstrated an almost complete inhibition of the mutagenicity of a cigarette smoke condensate and oral Swedish moist snuff. (3) EA also caused a decrease in the mutagenicity of a food mutagen. (4) In another very interesting study, EA inhibited the activities of certain enzymes in human immunodeficiency virus (HIV) and avian myeloblastosis virus. (5)


  1. Loarca Pina, G., et al, Mutat Res (1996) 360(1) p 15 21.
  2. Loarca Pina, G., ibid.
  3. Romert, L., et al, Mutat Res (1994) 322(2) p 97 110.
  4. Ayrton, A., et al, Food Chem Toxicol (1992) 30(4) p 289 95.
  5. Take, Y., et al, J Antibiot (1989) 42(1) p 107 15.

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