Antimutagenic agents such as Ellagic Acid inhibit the mutagenic process (a process where a cell could develop into a cancer).
Ellagic acid (EA) is a phenolic compound with antimutagenic and anticarcinogenic properties. It occurs naturally in some foods such as strawberries, raspberries, grapes, black currants and walnuts. (1) In this formula, EA is standardized at a level of 1% from raspberry extract.
When a cell is exposed to a mutagen and consequently assumes a mutagenic form, it may develop into a cancer. The value of antimutagnic agents such as EA, is that they inhibit the mutagenic process. In one study, the greatest inhibitory effect of EA on a potent mutagen occurred when they were incubated together. (2) In another study, EA demonstrated an almost complete inhibition of the mutagenicity of a cigarette smoke condensate and oral Swedish moist snuff. (3) EA also caused a decrease in the mutagenicity of a food mutagen. (4) In another very interesting study, EA inhibited the activities of certain enzymes in human immunodeficiency virus (HIV) and avian myeloblastosis virus. (5)
By Gene Bruno, MS, MHS – Dean of Academics, Huntington College of Health Sciences. Posted May 4, 2011.
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- Loarca Pina, G., ibid.
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- Take, Y., et al, J Antibiot (1989) 42(1) p 107 15.