Extra Virgin Olive Oil Reduced Blood Brain Barrier Permeability and Improved Clinical Dementia Rating Scores in Adult Subjects with Mild Cognitive Impairment

Written by Taylor Woosley, Staff Writer. 6 months daily consumption of 30 mL extra virgin olive oil significantly reduced p-tau 181 levels (p=0.05) and blood-brain barrier permeability (p<0.05), and improved WMS-IV logical memory test scores (p=0.05).  (more…)

Vitamin D Supplementation Reduces Depressive Symptoms in Subjects with Major Depressive Disorder

Written by Taylor Woosley, Staff Writer. Significant findings of this systemic review and meta-analysis of 41 papers with a total of 53,235 participants show that subgroup analysis in participants with clinically relevant depressive symptoms (including subjects with MDD) yielded a moderate effect favoring vitamin D supplementation (Hedges’ g = −0.604, 95% CI −0.802 to −0.406, p < 0.001, I2 = 78.4%).  (more…)

Selenium Supplementation Improves Glutathione Peroxidase Activity in Alzheimer’s Patients

Written by Taylor Woosley, Staff Writer. Analysis of a systemic review of 11 studies and a meta-analysis including 6 papers show that selenium supplementation increased MDA levels significantly by an average of 0.95 (0.44, 1.45) times (p = 0.0002). Furthermore, Se only supplementation significantly increased GPX activity by an average of 0.95 (0.59, 1.31) times (p = 0.00001).  (more…)

Higher Dietary Niacin Consumption Decreases Migraine Risk

Written by Taylor Woosley, Staff Writer. Results of the large cross-sectional study show that compared to individuals with lower niacin consumption Q1 (12.3 mg/day), the adjusted OR values for dietary niacin intake and migraine in Q3 (18.4-26.2 mg/day) and Q4 (26.3 mg/day) were 0.78 (95%CI: 0.66-0.92, p=0.004) and 0.74 (95%CI: 0.60-0.92, p=0.009), respectively.  (more…)

Effects of Melatonin for Delirium in Elderly Acute Heart Failure Patients

Written by Marlene Hollick, Ed.D., R.D. Based on a randomized, double-blind, placebo-controlled study exploring the effects of melatonin on delirium in elderly acute heart failure patients while in the ICU, results demonstrated that melatonin could reduce the incidence of delirium, average lengths of stay, and costs of hospitalization. (more…)

Dispositional Pessimism Associated with Lower Memory Scores in Older Adults

Written by Taylor Woosley, Staff Writer. Dispositional optimism observed in 26-year old subjects correlated with higher scores on matrix reasoning, while higher dispositional pessimism correlated with lower scores on matrix reasoning, vocabulary, and motor skills. 46-year old subjects with higher dispositional optimism correlated with higher memory scores.  (more…)

Higher Serum Lutein and Zeaxanthin Levels Associated with a Lower Risk of All-Cause Dementia

Written by Taylor Woosley, Staff Writer. Study findings using data from the NHANES III Survey (1988-1994) show that serum lutein+zeaxanthin was associated with a reduced risk of all-cause dementia, with an inverse relationship being noted between serum β-cryptoxanthin and all-cause dementia.   (more…)